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Antibiotic resistance
Wound infections
Nanotechnology
Antimicrobial peptides
 
Seek & Heal™ targeting
Targeting verification
Antimicrobial substance
Bactericide verification
Tissue friendly verification
 
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Seek & Heal™ Therapy for Antibiotic Resistance

 

Seek & Heal™ drug targeting

Drug targeting

Seek & Heal™ is one of few drug targeting projects
globally, and the only project of this type in Northern
Europe.

The technology is based on particles that selectively
adhere to bacteria. The particles do not adhere to
human healthy tissues. The particles encapsulate
a pharmaceutically active substance (drug).

After adhering to bacteria, the particles release the
drug. Various types of drugs may be incorporated
into the particles.

...read more

Selective therapies

Seek & Heal™ technology results in selective
treatment of bacteria and other foreign cells,
without affecting human healthy tissues.

The selectivity gives possibilities of new therapies
based on otherwise non-discriminating drugs.

Similarity to antibiotics

Antibiotics revolutionized antibacterial therapy
when they were introduced during World War II.
They selectively kill bacteria, without harming
human tissues.

Particles of Seek & Heal™ technology selec-
tively adhere to e.g. bacteria and release an
encapsulated drug. The drug hence treats the
bacteria, without affecting the rest of the body.

...read more

Antibiotic Resistance

Bacteria are rapidly becoming resistant to-
wards antibiotics, representing one of the
greatest threats to human health worldwide.

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Nanoparticles

As Seek & Heal™ particles are smaller than
bacteria, they easily find their targets.

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Product areas

A variety of substances can be encapsulated in
the Seek & Heal™ particles. A common feature
for all products is that the particles will adhere
to foreign cells like bacteria and not to human
healthy tissues.

Present focus areas are:

diagnostic tests for identification of bacteria.
products for wound therapy.

Wound therapy

A promising application area of Seek & Heal™
targeting includes disinfection of wounds.

Burn wounds, diabetic foot ulcers, leg ulcers and
surgical wounds are frequently infected. When the
infection is caused by resistant bacteria, human
suffering and hospital costs are significant.

...read more

The wound is washed with a solution containing
Seek & Heal™ particles, encapsulating an anti-
septic substance. The product kills bacteria in the
wound, without harming human healthy tissues.

...read more

Disinfection of a wound, using tissue selective
non-antibiotics, implies several advantages.
The infection is controlled without affecting the
wound healing and the risk of further spreading
resistant bacteria is decreased.

 

Four batches of nanoparticles