Seek & Heal™ drug targeting
Drug targeting
Seek & Heal™ is one
of few drug targeting projects
globally,
and the only project of this type in Northern
Europe.
The technology is based on particles that selectively
adhere
to bacteria. The particles
do
not adhere to
human healthy tissues. The particles encapsulate
a pharmaceutically active substance (drug).
After adhering to bacteria,
the
particles
release
the
drug. Various
types of drugs
may be
incorporated
into the particles.
...read more
Selective therapies
Seek & Heal™ technology results in selective
treatment
of bacteria
and other foreign cells,
without
affecting
human healthy
tissues.
The
selectivity gives possibilities of new therapies
based
on otherwise non-discriminating drugs.
Similarity to antibiotics
Antibiotics revolutionized antibacterial therapy
when
they were introduced during World War II.
They
selectively kill bacteria, without harming
human
tissues.
Particles of Seek & Heal™ technology selec-
tively
adhere to e.g. bacteria and release an
encapsulated drug. The drug hence treats the
bacteria,
without affecting the rest of the body.
...read more
Antibiotic Resistance
Bacteria are rapidly becoming resistant to-
wards antibiotics, representing one of the
greatest threats to human health worldwide.
...read more
Nanoparticles
As Seek & Heal™ particles
are smaller than
bacteria,
they easily find their targets.
...read more
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Product areas
A variety of substances can be encapsulated in
the
Seek & Heal™ particles. A common feature
for
all products is that the particles will
adhere
to
foreign
cells like
bacteria and
not
to
human
healthy
tissues.
Present focus areas are:
• diagnostic
tests
for identification of bacteria.
• products
for
wound therapy.
Wound therapy
A promising application area of
Seek & Heal™
targeting includes disinfection of
wounds.
Burn wounds, diabetic foot ulcers, leg ulcers and
surgical wounds are frequently infected. When the
infection is
caused by resistant
bacteria, human
suffering
and hospital costs are
significant.
...read more
The wound is
washed
with
a solution
containing
Seek & Heal™ particles,
encapsulating an anti-
septic substance. The product kills
bacteria in the
wound,
without
harming
human
healthy tissues.
...read more
Disinfection of a wound, using tissue selective
non-antibiotics, implies several advantages.
The
infection is controlled without affecting the
wound healing and the risk
of further
spreading
resistant bacteria is
decreased.
Four batches of nanoparticles |
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