Antiseptics in wounds
Background
Since the dawn of medical treatment,
it has been
realized that avoiding infections in wounds will
increase
the
probability
of patient survival.
During World War I antiseptics like Dakin's solution
and Dichloramine-T where used in wounds. Already
Alexander Fleming pointed out that antiseptics
were also toxic to human tissues.
When antibiotics were discovered as antimicrobials,
antiseptic substances became merely
historically
interesting.
Antiseptic substances - Not in wounds
Today, when antibiotics
are rapidly becoming
in-
efficient due to bacterial
resistance, antiseptics
is
one
way to tackle the
need to avoid infections.
Antiseptics are used
to eliminate
bacteria
e.g.
at
instrument surfaces and at intact
skin.
Antiseptics are quite effective in killing bacteria.
Unfortunately
they
are not selective, i.e. they
da-
mage
healthy
tissues as efficiently as bacteria.
The
damages
cause
prolonged
wound
healing
and
scar
formation.
Use of antiseptic
substances is therefore
avoided
in
modern
wound care.
Instead care today
relies
on
aseptic
techniques, i.e. one
tries to
avoid
contamination of bacteria
by working
in
a clean
environment.
Should infection occur, it is treated by antibiotics,
or
left for the patient's immune system to cure. |
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Targeting - Use antiseptics in wounds
By introducing selectivity to antiseptics, Seek
& Heal™ targeting from Microbionical permits
possibilities of new types of antiseptic
products.
The active
agent
is targeted towards
individual
bacteria cells or
towards
colonies
of
bacteria.
Seek & Heal™ targeting results
in
that
bacteria
are
exposed to
higher concentrations of anti-
microbial
substance
than
the patient's healthy
tissue.
During wound treatment, bacteria
are
damaged.
 ...read more
Blood and
healthy
tissues are left intact.
...read more
As a consequence of that bacteria are killed,
while
human tissues are left intact,
rapid healing
of the
wound without
scar formation is
expected.
Wound care due to selectivity
A therapy from Microbionical will allow
direct
anti-
septic
treatment of open
wounds.
This permits
• decrease risks of
infection
• control of resistant bacteria,
• reduction of antibiotic resistance,
• longer
intervals
between bandage
replacements
• less suffering for patients
• decreased hospital costs |
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