Disinfection of wounds
Tissue selective
non-antibiotic
product
To decrease patient suffering and save hospital
costs,
Microbionical develops Seek & Heal™, a
tissue selective,
non-antibiotic
product
for
disinfection of
wounds.
The
product consists of an antiseptic substance
encapsulated in particles that
selectively adhere
to
bacteria. After adhering to the bacteria,
the
par-
ticles
release the antiseptic substance.
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By the adhering and release processes,
bacteria
are
exposed to higher concentrations of the
anti-
septic substance,
compared to human tissue.
The product controls the infection without influen-
cing
the wound healing process. Also antibiotic
resistant bacteria are killed by
the antiseptic.
Background
Wound Infections
Burn care sites
Severe skin burns lead to immunosuppression
and easy paths for bacteria to enter
human
tissues and blood.
The patients are saved from mortal infections
by
heavy use of antibiotics.
Burn units are known as a source for outbreaks
of
multidrug resistant bacteria. Appearance of
MRSA,
multidrug resistant Pseudomonas and
Acineto-
bacter species and Vancomycin resistant Entero-
coccus species and S aureus were
all linked to
burn units. |
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Diabetic foot wounds
Diabetes is a rapidly growing disease. Diabetic
foot wounds are caused by improper
functioning
of blood circulation, decreased nerve
signaling
and probably also increased infection
sensitivity
diabetic's blood.
Diabetic
foot wounds frequently
become infected.
In the western countries about 160 000
leg ampu-
tations are annually caused by diabetic
foot wound
complications.
The costs for diabetic wound
treatment are
about
the same in all western
countries.
For Europe plus
USA, the annual direct costs are about
14 000
million Euro, corresponding to € 18 per capita..
Leg ulcers
Leg ulcers are caused by improper functioning of
blood circulation and therefore may require long
time to heal. About 2% of the population is affected.
Leg ulcer care annually cost about 4 800
million
Euro in the western countries.
Surgical site infections
In USA, about 2% of all surgical operations
are
followed by infection, despite presurgical
treat-
ment with
antibiotics. Annual costs for
infections
following surgery is
estimated
to $1 600 million.
Wound contamination
is mainly caused by
bacteria
entering
from
some other
place
at
the patient.
Due to bacterial resistance, the efficacy
of antibio-
tics
is rapidly declining. Surgical infections
will
gradually
become less
treatable using
present
methodology.
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