Wound
disinfection
A recently infected wound
contains a mixture of blood
components,
healthy tis-
sue
and bacteria.
A product for wound disin-fection should selectively
kill the bacteria,
while not
interfering with
the other components in
the wound liquid.
The diagram at right illu-
strate
survival
of Erythro-
cytes, i.e.
red blood cells,
when exposed to AMS,
an
antiseptic
substance, and
AMS encapsulated in two
separated batches of
Seek & Heal™ particles.
Concentration of
AMS is
indicated
within
brackets. |
 The
vertical
axis
represents percent
of cells not
harmed.
The horisontal
axis represent time, up
to about two hours. |
No damage to Erythrocytes
The diagram above illustrates that AMS, i.e. the
antimicrobial
substance
administered
without
Seek & Heal™
technology,
gave
a rather short,
concentration
dependent
Erythrocyte
survival
time.
A formulation from the first generation
of
carriers gave
an Erythrocyte survival
time
of
about
12 minutes
(E76).
Subsequent refinements of the Seek& Heal™ particles
gave
Erythrocyte
survival times of
about 25
(SH29)
and 100 minutes (SH59). |
